West indian people

On the lookout for people who can never catch Covid! Can there be?

Over a million people have received their Covid vaccines to build immunity to one of the deadliest diseases of all time, while a few others may have survived self-imposed lockdowns to stay the course. away from the clutches of this same pandemic.

It is a human tendency to protect oneself from dangers. The basic example of this was explained by Charles Darwin, how natural selection plays a bigger role in the evolution of human beings.

According to fundamental theories of biology, genes which have a better affinity of competition and survival with the change of environment, are preserved and preferred in the transfer of genetic information to the next generation.

But when a single bodily mechanism can select one particular gene over another, can it also create a genetic makeup in an individual to escape or be resistant to any infection caused by a pandemic virus.

> And we ask, can a person from birth resist the infamous Covid-19 virus?

Well, according to a group of international researchers, there is a complete chance that such people are genetically resistant to SARS-CoV-2 and a whole team has launched a search for these types across the world.

This is done to find hope of developing new drugs and new lines of treatment, in the times of desperation when the third wave begins to inflict greater pain on mankind.

In the UK alone, Omicron has caused more than 150,000 deaths to date.

Meanwhile, India has recorded nearly 1,68,000 new cases and 277 deaths so far, from a single new strain of an old virus.

And these scientists are looking for the same superpower in humans participating in this hunt in the future.

An immunogeneticist exclaims: “It’s a great idea. Really, a wise thing to do.

They launched this campaign in the form of a newspaper in Natural immunology.

Why can this new research and this new idea change the way things are going?

Since this virus has integrated well into our lives and living with the same virus has become the new normal, eliminating it will never be easy, but also, not impossible.

The team speculates that if they are able to identify these kinds of genes, if any, that protect these individuals from potential infection, it could lead to the development of virus-blocking drugs.

Such a range of drugs will not only dare to protect people against COVID-19 or its variants, but will also limit the spread of new infections.

Isn’t that overwhelming? How will it be undertaken?

As mentioned in the Nature: “The first step is to restrict the search to people who have been exposed, unprotected, to a sick person for an extended period of time, and who have not tested positive or have not developed an immune response against the virus. “

“Of particular interest are people who shared a house and bed with an infected partner – pairs known as discordant couples. “

But the idea is as difficult as it sounds: “The question is how to find these people. It’s very difficult. These are not for the faint of heart. “

If there is this trait in any part of Humanity, finding one and verifying it will not be easy. In addition, the success of this research is not completely guaranteed.

But one of the study’s authors is genuinely optimistic, saying: “Even if we identify one, it will be really major”.

And with greater progress underway, nearly 10 co-authors of the study have already recruited nearly 500 potential candidates from a range of countries, including India.

The co-author explains: “I didn’t think for a second that the people themselves, exposed and seemingly uninfected, would contact us. The goal is to have 1000 recruits.

Once the participants are definitive, their respective genomes will be screened by the Researchers and compared to those of infected people.

And candidate genes will be sought, in cell and animal models, to confirm any link with resistance.

But the challenge is to prove that these candidates have been previously exposed to the virus in previous Covid infections and with the vaccinations in place, it will be difficult to unmask any possible genetic resistance to the virus.

Are we sure we can find these lucky ones?

The human body is a mystery in itself. He can weave wonders.

There could simply be people with strong immune responses, or people with greater resistance in the cells lining inside the nose or maybe people with mutations to have possibly increased their genes that prevent the virus from spreading. replicate or produce new versions.

“We are convinced that we will find them”, explains the author.

The world is full of possibilities and so are we, a miraculous creature on the planet who can do anything: destroy the planet from which it draws its life or strive to save all of humanity from something unseen to come.


Source link